Leonberger
INQUIRY ON OSTEOSARCOMA IN LEONBERGER

BONE CANCER


We have lost several of our Leonbergers due to osteosarcoma. In my particular case, three of the six Leonbergers I have lost, have died because of that dreadful cancer. For over 15 years I have been persuaded that there is a strong genetic base favourable to the appearance of osteosarcoma. Today this genetic origin is not denied anymore and we are happy, Anne Voiry and me, to work on this study in collaboration with Antagène laboratories.

It is, however, the researchers' opinion, that although osteosarcoma relies on genetic predisposition, it will only appear following a triggering factor. It is the question of the role of the environment in the appearance or not of that cancer that touches leonbergers and many other breeds

So it was vital to, together with the genetic research work, conduct a study aiming to target what elements of the dog's environment were liable, with all due caution, to induce, or not osteosarcoma.

Therefore, whatever the breed, all dog owners who have endured the sad experience of osteosarcoma, can contribute to this inquiry. All dogs will benefit from the fact that this questionnaire casts the net wide.

I elaborated this questionnaire, basing myself on hypotheses coming from the lives of my three leonbergers deceased due to osteosarcoma. For each of them I have noted down potential causes, leads that deserved to be at least studied.

Violent bites in one case, important physical exercises in the other, an early neutering in the third one. I also based myself on similar observations from other owners. But I am open to all other suggestions or comments that could enrich our approach.

This questionnaire is divided into sections that look into the breed and genetic aspect, then the general environment: growth, physical activity, feeding, diseases and drug treatments, and finally eventual traumas (bites, shocks, fractures).

Dominique Félix - 24th of November 2007

This inquiry was initiated by Dominique Félix, breeder of the " Leonbergs des Neiges de Chantelouve ", in collaboration with Anne Voiry, breeder of the Bonnie Blue Flag, Antagène laboratories, Dr Anne Thomas, and CNRS of REnnes, Dr Catherine André about osteosarcoma in Leonbergers. We thank you for your help.

INQUIRY ON OSTEOSARCOMA IN LEONBERGERS

This inquiry was initiated by Dominique Félix, breeder of the " Leonbergs des Neiges de Chantelouve ", in collaboration with Anne Voiry, breeder of the Bonnie Blue Flag, Dr Anne Thomas of Antagène laboratories and Dr Catherine Andre, Specialist in Cancerology in CNRS of Rennes, about osteosarcoma in Leonbergers. We thank you for your help.....

Your name :
Your address email:
Your full post address : I authorize the use of this data:
Yes
No

 

COMMEMORATIVES.
Full name of the dog and identification (Nr Breed, and Tat or insert):
Breed:
Age of appearance of osteosarcoma : Location of osteosarcoma : (please, with the name exact of the bone concerned)
Symptoms, general signs (pain, lameness, swelling, heat, licking, another signs...): Another commentaries...

 

Method of diagnosis:
Examination Biopsy:
Radiography
Another (please, explain)
Name and address of the veterinarian that followed the dog during his illness : Names and addresses of the laboratories, specialized in cancerologie centers that followed the dog for the diagnosis and therapy :

 

GENDER
Male Breeder Castrated Age of castration
Female Breeder Spayed Age of spaying in rapport with the first heat cycle (precise if it was before)
Time between last gestation an appearance of osteosarcoma : Eventual commentaries :

 

FOLLOWED TREATMENTS..
No treatment Chemotherapy Radiotherapy Amputation
Other treatments. Please clarify if there are chemotherapy, radiotheray and amputation, how... Palliative care. Clarify. :
Survival time : Commentaries about treatments :
Died the dog? Cause of death? Commentaries :

 

MORPHOLOGY AND TYPE.
Lean, slender dog Squat, stocky dog Adult weight: Height of the withers :
Bone, frame: Heavy Slender Medium
Stand : Correct Feet turning out Commentaries :

 

GROWTH.
Growth was slow: Fast Easy Difficult
During the growth the dog was fed with: It was given the following complements and additives:

 

PHYSICAL ACTIVITY (regularly).
Playing, running and jumping: Often Seldom From what age to what age, and how frequently:
Walks with a leash: Often, calmly. Seldom, never From what age to what age, and how frequently?
Walks without a leash: Ran a lot and for a long time Walked and followed calmly From what age to what age, and how frequently?
Obedience training: Regularly Never From what age to what age, and how frequently?
Agility training: Regularly Never From what age to what age, and how frequently: ?
Water: Swam often: Swam never: From what age to what age, and how frequently:
Generally: It was a lively and very active dog, maybe a daredevil It was a calm, peaceful dog, cautious and moderate: Commentaries

 

FEEDING .
Industrial type dry food : Home cooked meals (what types of meat, vegetables, cereals): Complements (vitamins, oils, trace elements, etc, and in what way ?) Other kinds of feeding :

 

DISEASES, TREATMENTS
Hypothyroïdism : Hypocortscism : Other known immune deficiencies Other diseases (piroplasmosis, bloat, skin, heart, parasitism.. etc) Please, clarify :
Drugs given over a long time: Antibiotics, Anti-inflammatory medications, others.... Thank you for clarifying. Antibiotics: Anti-inflammatory medications: Other drugs :
Vaccinations regularly. Clarify. Regular anti-parasitic (worming treatments external anti-fleas, ticks, etc.). Specify.

ENVIRONMENT

The dog has been exposed to environmental nuisance type radiation, asbestos, smoke, agricultural products (pesticides, growth hormones ..) or other industry that you consider important?

 

ACCIDENTS, TRAUMAS

Previous traumas at osteosarcoma location: Shock(s), blow(s): : Fall(s): Wound(s):
Bite(s): Fracture(s): Other cases and repeat of trauma: How many times before the osteosarcoma ?

 

PSYCHOLOGY, TEMPERAMENT.
Sensible dog, easy stressed Quiet dog, never stressed Dog shy, remote, reserved Dog hyper-active, dynamic, shaked
Phlegmatic dog, no sportive He had a stress (fight, losing a partner or arrival of a new companion, separation, moving ..)? Indicate which: Other comments about his character that will be helpful:
Before sending, please describe the evolution of the disease: discovery, veterinary detection, evolution, and everything else that could seem useful.

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